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Common Genetic Variation May Underlie Different Mental Illnesses

An international group of psychiatric researchers has identified a 15% overlap between schizophrenia and bipolar disorder in heritability attributable to common genetic variation, according to a study by the Cross Disorders Group of the Psychiatric Genomics Consortium, published online in Nature Genetics August 11.

The group of more than 300 researchers in 20 countries used genomewide genotype data from thousands of people and compared them with control subjects. Besides the relationship between schizophrenia and bipolar disorder, there was a 10% overlap in heritability between bipolar disorder and depression, a 9% overlap between schizophrenia and depression, and...

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Published By: Psychiatric News - Wednesday, 14 August