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Brain Scans Reveal Changes Linked to PMDD

A new study supports the clinical relevance of the proposal that dorsolateral prefrontal cortex dysfunction represents a substrate of risk for premenstrual dysphoric disorder (PMDD). When women with PMDD and women without the disorder were given a cognitive task, the dorsolateral prefrontal cortex of the former became significantly more activated than did the prefrontal cortex of the latter.

So reports Karen Berman, M.D., of the National Institute of Mental Health Intramural Research Program, and her colleagues in AJP in Advance. It thus looks as though the dorsolateral prefrontal cortex "plays an important role...

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Published By: Psychiatric News - 2 days ago