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Study Links Antipsychotics to Cortical Loss in Patients With Schizophrenia

Although it is well established that patients with schizophrenia have deficits in cortical gray matter, a meta-analysis published in Biological Psychiatry suggests that cumulative antipsychotic intake and the type of antipsychotic a patient with schizophrenia takes may influence the degree of gray matter loss over time.Researchers from the University of Brescia School of Medicine in Italy led an retrospective study to determine if changes in cortical gray matter differ between patients with schizophrenia who take first-generation antipsychotics (FGAs) and those who take second-generation antipsychotics (SGAs). The researchers compiled data from...

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Published By: Psychiatric News - Friday, 11 September, 2015

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