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Novel Compound Found to Be Safe, Effective at Reducing Symptoms of MDD

The results of a clinical trial published yesterday in Molecular Psychiatry suggest that a novel compound found to increase the production of cells may help to relieve symptoms of major depressive disorder (MDD).Previous animal studies have suggested that NSI-189, a benzylpiperizine-aminopyridine, stimulates neurogenesis in the hippocampus. In the current study, a group of researchers led by Maurizio Fava, M.D., director of the Clinical Research Program at Massachusetts General Hospital, evaluated the effectiveness, safety, and tolerability of NSI-189 in a phase 1B clinical trial that included 24 patients with recurring symptoms...


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Published By: Psychiatric News - Wednesday, 9 December, 2015

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