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Metformin May Normalize Antipsychotic-Induced Lipid Imbalance in People With Schizophrenia

Patients with schizophrenia who take antipsychotics commonly experience serious adverse metabolic effects including dyslipidemia—a condition characterized by abnormally high levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), or triglycerides, as well as abnormally low levels of high-density lipoprotein cholesterol (HDL-C). A study published this week in Molecular Psychiatry now suggests that the type 2 diabetes medication metformin may be able to help normalize lipid levels in this patient population.Although there is evidence to suggest metformin decreases triglycerides and LDL-C in patients with diabetes, it was unknown whether the medication would...

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Published By: Psychiatric News - Friday, 29 January, 2016

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