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FDA Approves Vraylar for Treatment of Schizophrenia and Bipolar Disorder

The Food and Drug Administration (FDA) last week approved Vraylar (cariprazine), a dopamine D2/D3 receptor partial agonist, as a treatment for schizophrenia and bipolar disorder in adults.The approval was based on a set of six controlled clinical trials that included over 2,700 adults with bipolar disorder or schizophrenia. Vraylar was shown to reduce the symptoms of both disorders compared with placebo, and was fairly well tolerated, with the most commonly reported adverse reactions being extrapyramidal symptoms and restlessness (akathisia).Vraylar is one of the first FDA-approved antipsychotics that has demonstrated efficacy...


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Published By: Psychiatric News - Monday, 21 September, 2015

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